Karin Shmueli is interested in developing Magnetic Resonance Imaging (MRI) techniques to increase image contrast and resolution by exploiting new contrast mechanisms. The current goal of her research programme is to characterise frequency and susceptibility contrasts and to develop and translate MRI techniques exploiting these mechanisms to improve disease diagnosis and monitoring of therapies. Conventional MRI uses only the signal magnitude, but utilising the frequency (or phase) of the MRI signal has dramatically improved visualisation of tissue structure and can reveal tissue composition.
During her previous post at the USA National Institutes of Health, she developed new methods to calculate tissue magnetic susceptibility maps from MRI frequency images. MRI tissue Susceptibility Mapping is an exciting technique and a rapidly growing research area. Together with her research group and collaborators, she now aims to unlock the potential of these MRI frequency and susceptibility methods to generate clinical MRI biomarkers of disease.