21st Century healthcare is facing a crisis due to rising life expectancy and an increase in the incidence of many age-related diseases that currently have no cure. Illnesses such as Alzheimer’s, Parkinson’s, diabetes, heart failure and blindness place enormous financial burden on healthcare providers and significantly reduce quality of life for sufferers. Regenerative medicine is an emerging field that aims to utilise the power of stem cells and tissue engineering to overcome these diseases.
However, translating the discovery science into manufacturable products has so far been challenging and so multi-disciplinary engineers are urgently needed to bring new engineering solutions to the manufacture of these complex medical products. UCL engineers will learn about these emerging medicines and then focus their engineering skills to appraise existing devices, tools and technologies for processing and analytics that are used during manufacture.
Manufacturing for living cell products, along with advanced biomaterials processing for tissue engineering and drug delivery, will be assessed in the first two modules. In the final module, students will undertake a design-based project to create a new manufacturing process for a typical regenerative medicine product, with feedback from potential future employers including industrialists and the Cell Therapy Catapult. The outcome for the student will be a strong grounding in the application of manufacturing tools for new medicines that will define 21st Century healthcare.
Module 1 (Year 2, Term 2) – Manufacturing Regenerative Medicines from Lab Bench to Industry
The aim of the module is to introduce engineering students to tools and technologies that underpin manufacture of regenerative medicine products, which are becoming increasingly important for 21st Century healthcare and which will require talented multi-disciplinary engineers to create sustainable manufacturing pathways for.
Module 2 (Year 3, Term 1) – Advanced Materials, Devices and Manufacturing Processes for Regenerative Medicines
Biomaterials and their utility in regenerative medicine as substrates for cell culture and in fabrication of miniature and microfluidic devices that can provide enhanced process understanding to regenerative medicines processing challenges. Wider aspects of manufacturing that are essential for translation will be considered including facility and infrastructure requirements and storage of living cell material.
Module 3 (Year 3, Term 2) – Design and Manufacture of Regenerative Medicine Drug Products
The aim of the module is to provide students with a working understanding of regenerative medicines manufacture and the considerations regarding infrastructure, principles of good manufacturing practice and the wider environmental and economic impact of their manufacture. This will provide students with the skills that would be highly desirable by a growing regenerative medicines manufacture industry and the Cell Therapy Catapult.
Dr Qasim Rafiq
Dept Biochemical Engineering
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